Liver fibrosis

Fibrosis of the liver is a process in which excess connective tissue forms in the liver as a response to damage. This damage can be caused by a variety of factors, such as viral infections (such as hepatitis B and C), alcohol, toxic substances, metabolic disorders, and autoimmune diseases. Fibrosis can gradually impair liver function as excess connective tissue replaces healthy liver cells and prevents normal blood flow to the liver.

Cirrhosis of the liver is a more advanced stage of fibrosis in which there is extensive replacement of normal liver tissue with scar tissue, leading to significant impairment of liver structure and function. Cirrhosis can lead to serious complications such as portal hypertension (increased pressure in the portal vein), ascites (accumulation of fluid in the abdominal cavity), bleeding from enlarged veins (varices) in the esophagus and stomach, liver failure, and hepatocellular carcinoma (liver cancer).

The main difference between fibrosis and cirrhosis lies in the extent and severity of liver damage. While fibrosis can be reversible in some cases if the cause of the damage is removed, cirrhosis is usually irreversible and may require more complex treatment, including a liver transplant in advanced cases. Recognition and proper management of liver fibrosis can help prevent its progression to cirrhosis.